1. Home
  2. Health
  3. Allergies

What Are Antihistamines?

Antihistamines are drugs that prevent allergic reactions. Here's more information on antihistamines and the allergies they protect against.

Transcript: What Are Antihistamines?

What Are Allergens?

An allergy occurs when the body reacts to substances it views as harmful. The substances, such as tree pollen or dust mites, are called allergens. Following the body's first exposure to an allergen, white blood cells produce antibodies that prepare the immune system for the next encounter with the same allergen. Antibodies attach themselves to mast cells--special cells found in the tissues of the respiratory and digestive systems.

How Allergens Affect the Immune System

Subsequent exposure to even a small amount of the allergen triggers the mast cells to release histamine. When histamine is released, it attaches to the receptors of nearby cells. These receptors interact with other substances in the body and cause nearby blood vessels to swell and secrete excess fluid-causing symptoms such as sneezing, runny nose, and watery eyes.

What Are Antihistamines?

Antihistamines are drugs that can protect cells from some of the allergic effects caused by histamine. By attaching themselves to the receptors, these drugs can prevent cell receptors from binding to histamine. This prevents histamine from causing the chemical reactions in the cells that produce allergy symptoms.

Copyrighted animations provided by Blausen Medical.

FREE Newsletters

Want to Make Videos? Tell Us!

We comply with the HONcode standard for trustworthy health information: verify here.
  1. Home
  2. Health
  3. Allergies

©2009 About.com, a part of The New York Times Company.

All rights reserved.